Co enzyme Q-10

CoQ10 is naturally orange and found in most cells in the body. CoQ10 helps support cellular energy production in the mitochondria – the powerhouses of most cells. The highest concentrations of cellular mitochondria are found in the hardest working cells in the body, such as the heart, making CoQ10 an important nutrient to help support heart function. Moderate amounts of CoQ10 are found in foods, but the primary source of CoQ10 in the body is produced by the body itself. CoQ10 levels decrease with age and some cholesterol-lowering statin drugs can reduce CoQ10 production, which is why supplementing may be helpful to replenish CoQ10 levels in the body.
After the age of 30, natural levels of CoEnzymeQ10 (CoQ10) begin to diminish. By the age of 70, your CoQ10 levels may be critically low. Further loss of CoQ10 may come from stress, illness and medications such as statin drugs, oral hypoglycemic drugs and beta-blockers. While many doctors fail to inform you of these facts, many alternative practitioners believe that, given CoQ10’s potential benefits and good safety record, most people over the age of 40 would be wise to take CoQ10 supplements. The fact is that every cell and system is distressed by an energy shortage due to insufficient CoQ10.
Without adequate CoQ10, cells cannot make the energy they need to sustain themselves. Eventually, your whole body suffers the malaise of low-energy production. CoQ10 is an essential component of every cell, and supplemental CoQ10 has a wide range of potential uses. CoQ10, also known as ubiquinone, is a cellular energy booster and a powerful antioxidant, first identified in 1957 and widely used in Japan. It is a powerful fat-soluble vitamin-like substance synthesized in the membranes of cells. It is found primarily in mitochondria, the cells’ centers of energy production, and is an essential part of the energy-producing process known as the electron transport chain. It acts as a kind of spark plug, assisting in the generation of adenosine triphosphate (ATP) the body’s basic energy currency.
CoQ10 is most highly concentrated in heart muscles because of the high energy needs there. Research suggests that CoQ10 may be beneficial for improving many aspects of cardiovascular health.1 Given CoQ10’s essential role in maintaining heart health, it’s alarming to realize that the most widely-prescribed cholesterol-lowering statin drugs can severely deplete CoQ10.2
CoQ10 can also energize brain cells. The brain is especially compromised by a deficit of CoQ10. Reduced levels of CoQ10 (and ATP) occur as the brain ages. Studies show that replenishing CoQ10 supports the brain and may improve mental functions.
One problem with CoQ10 is that it’s not always well absorbed within the body. However, research shows that combining CoQ10 with piperine, a compound found in black pepper, significantly enhances CoQ10 absorption by over 30%.3
Scientific References:
1. J Nutr Biochem 2000;11: 109-113.
2. Altern Med Rev 1996;1(3):168-175.
3. 3. Arch Neurol 2004;61: 889-92.

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